Elimination of Thallium in Rats as Influenced by Prussian Blue and Sodium Chloride
- 1 August 1976
- journal article
- research article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 39 (2) , 256-261
- https://doi.org/10.1111/j.1600-0773.1976.tb03177.x
Abstract
The effect of Prussian Blue in protecting rats against lethal doses of thallium was investigated. Treatment with Prussian Blue increased the survival of rats from 0% to 50%. The elimination rate of thallium was increased in all the tissues studied, including the brain. Faecal thallium excretion was increased about three–fold. Treatment with hypertonic sodium chloride improved the short–term survival but the total mortality was unchanged.Keywords
This publication has 7 references indexed in Scilit:
- Thallium inhibition of ouabain-sensitive sodium transport and of the (
Na )-ATPase in human erythrocytesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1975 - Interaction of thallous ions with the cation transport mechanism of erythrocytesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1973
- DANGEROUS REDISTRIBUTION OF THALLIUM BY TREATMENT WITH SODIUM DIETHYLDITHIOCARBAMATEActa Medica Scandinavica, 1971
- PRUSSIAN BLUE IN THERAPY OF THALLOTOXICOSISActa Medica Scandinavica, 1971
- Ferric-cyanoferrate (II): An effective antidote in thallium poisoningEuropean Journal of Pharmacology, 1969
- Diminution of Radiocaesium Body-burden in Dogs and Human Beings by Prussian BlueInternational Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1966
- The Effect of various Substances on the Excretion and the Toxicity of Thallium in the Rat.Acta Pharmacologica et Toxicologica, 1956