EFFECT OF CYTOSTATICS ON SOME PLATELET FUNCTIONS INVITRO .6. VINBLASTINE

1 January 1978

journal article
research article

Vol. 25 (5) , 625-629

Abstract

The influence of vinblastine on principal functions of [human] blood platelets in vitro (adhesion, aggregation, platelet release reaction, membrane stabilization) was followed using an extended system of laboratory examinations. The concentration of vinblastine which is higher than the average therapeutic dose (10-5 M) inhibited the functional ability of platelets so that it might cause a thrombopathic disorder.

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