The Genetic Epidemiology of Irrational Fears and Phobias in Men

Abstract
FAMILY STUDIES suggest that phobias are familial,1-6 but cannot clarify the origin of this family resemblance. Twin studies of self-reported fears consistently have suggested a significant role for genetic factors.7-11 By contrast, twin studies of clinically defined phobias have, with one exception, suffered from very small samples sizes with resultant low power to discriminate alternative models of familial transmission.12-14 This exception is our previous study of phobias in female-female twins from the Virginia Twin Registry.15-17

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