FIXATION OF THE VOCAL CORDS IN ACROMEGALY

1 October 1950

journal article
research article
Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery

Vol. 52 (4) , 608-617
https://doi.org/10.1001/archotol.1950.00700030632008

Abstract

ACROMEGALY was described as a disease in 1885 by Pierre Marie.¹ Changes in the larynx have long been a part of the description of the syndrome. Several observers, Chappell,² Neufeld,³ Jackson⁴ and others, described hypertrophy of the mucous membrane, rotation and enlargement of the cartilages and other distortions in the larynx in cases of acromegaly. Fixation of the vocal cords has not been described previously in this disease, and we were able to find only 2 previous reports which suggest it. Chappell² in 1896 described a case of acromegaly in which the patient had a narrow airway and died of asphyxia before he could be presented before a medical meeting. Jackson⁴ reported a case in 1918 in which tracheotomy was necessary for a narrowed airway due to overgrowth of tissues. Fixation of the vocal cords has been observed by us in 2 cases encountered in rapid succession and these

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