Experimental tracheal homografting

Publisher Website
Google Scholar
Abstract
Factors which influence the fate of homotransplanted tracheal segments [in cats] are: the width of the transplant compared with that of the host animal; length of the transplant; possible infection or hematoma; surgical technique; and histological compatibility of the 2 animals. Refinements in surgical technique and elimination of infection can lead to a successful outcome with regard to transplantation of short segments of trachea containing up to 6 rings of cartilage. The trachea must be considered as a composite graft, and potential antigenicity of the surrounding soft tissues may be underestimated. The dissolution of cartilage consistently observed in these experiments can probably be explained on a vascular basis, but it is possible that phagocytosis in the tracheal cartilaginous arches of the graft is a rejection phenomenon and that its elimination or suppression may extend the survival time of the graft.

This publication has 6 references indexed in Scilit: