The molecule role ontology: an ontology for annotation of signal transduction pathway molecules in the scientific literature
Open Access
- 1 August 2004
- journal article
- Published by Wiley in Comparative and Functional Genomics
- Vol. 5 (6-7) , 528-536
- https://doi.org/10.1002/cfg.432
Abstract
In general, it is not easy to specify a single sequence identity for each molecule name that appears in a pathway in the scientific literature. A molecule name may stand for concepts of various granularities, from concrete objects such as H-Ras and ERK1 to abstract concepts or categories such as Ras and MAPK. Typically, the relations among molecule names derive a hierarchical structure; without a proper way to handle this knowledge, it becomes ever more difficult to develop a reliable pathway database. This paper describes an ontology that is designed to annotate molecules in the scientific literature on signal transduction pathways.Keywords
Funding Information
- Japan Science and Technology Agency
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