Cerebrospinal Fluid and Serum Ampicillin Levels in Bacterial Meningitis Patients after Intravenous and Intramuscular Administration
- 31 August 1981
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Infectious Diseases
- Vol. 13 (3) , 237-238
- https://doi.org/10.3109/inf.1981.13.issue-3.13
Abstract
28 patients with bacterial meningitis received ampicillin by the intramuscular (IM) route and 16 patients by the intravenous (IV) route. The mean cerebrospinal fluid (CSF) ampicillin levels were similar in the two groups 1 h after a dose given on the first or second day of treatment, but they were higher in the IM group on both days 4 h after a dose. CSF/serum ratios were similar in both groups but considerably higher at 4 h than at 1 h.This publication has 4 references indexed in Scilit:
- The value of Epicillin and Ampicillin in the Treatment of Meningococcal and Pneumococcal MeningitisScandinavian Journal of Infectious Diseases, 1976
- Ampicillin in Haemophilus influenzae MeningitisAmerican Journal of Diseases of Children, 1975
- Spectra of Susceptibility of Neisseria meningitidis to Antimicrobial Agents In Vitro 1Applied Microbiology, 1970
- Ampicillin in the treatment of acute suppurative meningitisThe Journal of Pediatrics, 1966