Lipid Metabolism of Two Highly Inbred Strains of Mice.
- 1 February 1966
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 121 (2) , 343-346
- https://doi.org/10.3181/00379727-121-30774
Abstract
Summary Differences in the metabolism of 2 highly inbred strains of mice were studied. There was a higher level of FFA in the plasma of the A/Fn strain mouse as compared to the I/Fn, although measurements of FFA release in vitro revealed no differences in the rate of mobilization per unit weight of adipose tissue. Ketone body production by liver slices was greater in the I, and in both strains was inversely related to the hepatic glycogen content. Tripalmitin-C14 oxidation to C14O2in vivo was more marked in the I than in the A, while fat retention was greater in the A. The simultaneous feeding of a 25% glucose-50% starch solution markedly depressed CO2 output from tripalmitin in the I strain and caused an enhanced output in the A.Keywords
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