TOTAL SYNTHESIS OF THE RACEMIC FORM OF THE SECOND JUVENILE HORMONE (METHYL 12-HOMOJUVENATE) FROM THE CECROPIA SILK MOTH
- 1 April 1969
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 62 (4) , 1005-1009
- https://doi.org/10.1073/pnas.62.4.1005
Abstract
Methyl cis -10-epoxy-3,7,11-trimethyl- trans,trans -2,6-tridecadienoate has been stereoselectively synthesized in 12 steps starting from methyl trans -γ-bromo-β,β-dimethylacrylate and 1-acetyl-1-methylcyclopropane. The final product proved to be identical with the second, less abundant juvenile hormone (methyl 12-homojuvenate) isolated from the Cecropia silk moth. The biological activities of the compound were evaluated in various insects.Keywords
This publication has 4 references indexed in Scilit:
- THE TWO JUVENILE HORMONES FROM THE CECROPIA SILK MOTHProceedings of the National Academy of Sciences, 1968
- Juvenile hormone activity of structurally unrelated compoundsJournal of Insect Physiology, 1965
- Prothoracotrophic activity of compounds that mimic juvenile hormoneJournal of Insect Physiology, 1965
- A Highly Purified Preparation of Juvenile Hormone from the Silk Moth Hyalophora cecropia L.Nature, 1965