Bcl-xS can form homodimers and heterodimers and its apoptotic activity requires localization of Bcl-xS to the mitochondria and its BH3 and loop domains

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Abstract
Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis. It provides a single accessible source of information for both scientists and clinicians, keeping them up-to-date with advances in the field. It encompasses programmed cell death, cell death induced by toxic agents, differentiation and the interrelation of these with cell proliferation.