Mycoplasma Pneumoniae and Viral Infections in Childhood Asthma

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Abstract
The association of respiratory viral infections and acute recurrence of wheezing were studied in 121 asthmatic children in the course of 143 hospital admissions. Evidence of viral or mycoplasma-pneumoniae infctions was sought from serology and/or virologic studies of nasal aspirates. In 46 of these admissions (32 per cent), a respiratory viral or mycoplasma pneumoniae infection was documented. Twenty of these 46 admissions (42 per cent) were associated with mycoplasma-pneumoniae infection. Parainfluenza virus infection was the next commonest associated infection, accounting for 12 admissions (25 per cent) followed by the respiratory syncytial viruses (11 admissions, 23 per cent). Influenza A virus and Rhinovirus were found in four admissions (8 per cent) each and adenovirus in three (6 per cent). We conclude that mycoplasma-pneumonia and respiratory viruses are common precipitants of wheezing episodes in asthmatic children in Singapore.

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