COGNITIVE FUNCTION AND REGULAR DIALYSIS TREATMENT

  • 1 January 1983
    • journal article
    • research article
    • Vol. 19  (4) , 188-192
Abstract
The purpose of this investigation was to assess the intellectual function of [uremia] patients on regular dialysis treatment by using neuropsychological tests such as the Wechsler Adult Intelligence Scale (WAIS) and the Wechsler Memory Scale (WMS). Studies were performed on 54 patients; 21 patients were retested after at least 12 mo. No relationship was found between the neuropsychological scores and the blood levels of small molecules, the Hb concentrations, the serum aluminium levels and the levels of formal education. An impairment of neuropsychological performance was found, mainly for memory function, related to the duration of dialysis and, possibly, to parathormone levels. Apparently, standard hemodialysis strategies are not able to prevent the development of intellectual impairment in uremic patients, and the WMS could be used as a sensitive objective measure of the comparative adequacy of various long-term dialysis treatments.

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