Current concepts of the mechanism of acute inflammation in gouty arthritis
- 1 March 1975
- journal article
- review article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 18 (2) , 129-134
- https://doi.org/10.1002/art.1780180208
Abstract
The acute gouty attack develops after free crystalline monosodium urate crystals appear in the joint cavity (1). Recent developments in the investigation of urate crystal‐induced inflammation have led to a better understanding of the pathogenesis of acute gouty arthritis. The purpose of this review is to summarize present concepts concerning the mechanism of the acute gouty attack.Keywords
This publication has 35 references indexed in Scilit:
- A Method for Assessing thein vitroChemotactic Response of Neutrophils Utilizing51FR-Labeled Hliman LeukocytesImmunological Communications, 1972
- The interaction of monosodium urate with connective tissue componentsJournal of Clinical Investigation, 1970
- Polymorphonuclear leukocyte motility in vitro. III. Possible release of a chemotactic substance after phagocytosis of urate crystals by polymorphonuclear leukocytesArthritis & Rheumatism, 1969
- Hageman Factor and Acute Gouty ArthritisArthritis & Rheumatism, 1968
- Genetic studies in primary goutJournal of Clinical Investigation, 1968
- Suppression of urate crystal‐induced canine joint inflammation by heterologous anti‐polymorphonuclear leukocyte SerumArthritis & Rheumatism, 1968
- Breakdown of cartilage proteinpolysaccharide by lysosomesArthritis & Rheumatism, 1968
- Uric Acid in Human Plasma: V. Isolation and Identification of Plasma Proteins Interacting with UrateScandinavian Journal of Clinical and Laboratory Investigation, 1966
- Suppression of metabolic accompaniments of phagocytosis by colchicineArthritis & Rheumatism, 1965
- Total hemolytic complement (CH50) and second component of complement (C′2hu) activity in serum and synovial fluidArthritis & Rheumatism, 1965