Catalyzed Asymmetric Arylation Reactions
Top Cited Papers
- 14 September 2001
- journal article
- review article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 40 (18) , 3284-3308
- https://doi.org/10.1002/1521-3773(20010917)40:18<3284::aid-anie3284>3.0.co;2-u
Abstract
Addition and substitution reactions with carbon nucleophiles are fundamental processes in organic synthesis, and the development of general catalytic asymmetric variants thereof is still a major challenge today. In contrast to enantioselective alkyl transfer reactions, the corresponding arylations have not yet reached a high level of maturity. The existing protocols are either of no general applicability or are limited in terms of selectivity. This article summarizes established routes for catalytic asymmetric aryl transfer together with the latest developments in this area. The scope and limitations of this reaction are discussed.This publication has 270 references indexed in Scilit:
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