AN ALGORITHM FOR DETERMINING GESTATIONAL-AGE FROM UNCONJUGATED ESTRIOL LEVELS
- 1 January 1980
- journal article
- research article
- Vol. 56 (5) , 649-655
Abstract
Between the 30th-40th wk of gestational age (GA), plasma unconjugated estriol concentrations plotted as logarithmic function of GA describe a complex bimodal curve. The maximum concentrations for the 1st peak occur at .apprx. 34 wk GA, those for the 2nd peak occur at .apprx. 38 wk GA and a between-mode nadir occurs at 35 wk GA. Using the close relationship between the features of this curve and GA, a computerized algorithmic curve analysis is devised for the estimation of GA during the 3rd trimester of pregnancy. This report describes the algorithm, its clinical application and its preliminary performance.This publication has 4 references indexed in Scilit:
- Interrelationships of Circulating Maternal Steroid Concentrations in Third Trimester Pregnancies. II. C18and C19Steroids: Estradiol, Estriol, Dehydroepiandrosterone, Dehydroepiandrosterone Sulfate, Δ5-Androstenediol, Δ4-Androstenedione, Testosterone, and DihydrotestosteroneJournal of Clinical Endocrinology & Metabolism, 1979
- Subhourly Variability of Circulating Third Trimester Maternal Steroid Concentrations as a Source of Sampling ErrorJournal of Clinical Endocrinology & Metabolism, 1978
- Sonar biparietal diameterAmerican Journal of Obstetrics and Gynecology, 1976
- Serum unconjugated estriol levels in the third trimester and their relationship to gestational ageAmerican Journal of Obstetrics and Gynecology, 1976