Effect of Intraventricular Glutamate on ACTH Release
- 1 January 1975
- journal article
- research article
- Published by S. Karger AG in Neuroendocrinology
- Vol. 18 (2) , 213-216
- https://doi.org/10.1159/000122400
Abstract
Sodium glutamate infused into the 3rd ventricle is a potent stimulus of ACTH release, as shown by the rise in plasma corticosterone levels. Glutamate failed to consistently increase the plasma corticosterone level in rats with deafferentation of the medial basal hypothalamus (MBH). We suggest that intraventricular glutamate interferes with central nervous function outside the MBH and stimulates ACTH release via afferent neural pathways.Keywords
This publication has 0 references indexed in Scilit: