Asymmetric Reduction of Chiral Pyruvamide with Sodium Borohydride
- 1 January 1983
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 56 (1) , 298-301
- https://doi.org/10.1246/bcsj.56.298
Abstract
Several amides of pyruvic acid with (S)-amines were reduced with sodium borohydride (NBH) in several alcohols and N-[(R)-lactoyl]-(S)-amines were obtained in excess. When the reductions were carried out in methanol or ethanol in the presence of metallic salt, N-[(S)-lactoyl]-(S)-amines were obtained in asymmetric yields up to 22%.This publication has 7 references indexed in Scilit:
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