Continuous maturation of proliferating erythroid precursors

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Abstract
Published steady-state cell kinetic (mitotic and DNA synthesis phase) data from the recognizable proliferating erythroid precursors in humans, rats and guinea pigs and human neutrophilic precursors were examined for consistency with a continuous maturation-proliferation model of the cell cycle. These data were completely consistent with the hypothesis that maturation between morphological compartments may take place at any point in the cell cycle. A number of compartmental parameters are derived under this assumption.