OSTEOARTHRITIS

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Abstract
Osteoarthritis, also known as hypertrophic arthritis, arthritis deformans, senescent arthritis, and degenerative joint disease, is a disease of unknown cause. Because tissue degeneration with aging is the most significant factor in the development of the disease, it has been recommended by the American Rheumatism Association that the disease be referred to as degenerative joint disease; I shall refer to it as such. Degenerative joint disease is the commonest type of arthritis, accounting for 25 to 30% of all patients seen in the average arthritis clinic. It may occur locally in a single joint or it may be generalized. It may be primary with no known precipitating cause or it may develop secondary to a known causative factor. In all cases, the pathological process is the same; basically there occurs a wearing away of cartilage, with a reactive proliferation of both cartilage and bone. This results in mechanical impairment of the

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