The influence of α-linolenic acid (18: 3ω3) on the metabolism of γ-linolenic acid (18: 3ω6) in the rat
- 1 July 1977
- journal article
- research article
- Published by Cambridge University Press (CUP) in British Journal of Nutrition
- Vol. 38 (1) , 137-140
- https://doi.org/10.1079/bjn19770069
Abstract
1.Essential fatty acid-deficient rats were fed γ-linolenic acid (18:3ω6) at 2 % dietary energy and α-linolenic acid (18:3ω3) at 0, 1.6, 2.8 and 4.0 % of the dietary energy. 2.18:3ω3 at 1.6% apparently inhibits the synthesis of the C20 and C22 ω6 long-chain polyunsaturated fatty acids (ω6 LC-PUFA) metabolized from 18:3ω6. 3.However, increasing the dietary levels of 18:3ω3 from 1.6 to 4.0% has no further influence. 4.The results suggest that dietary 18:3ω6 is an efficient precursor for the ω6 LC-PUFA synthesis even in the presence of 18:3ω3.This publication has 5 references indexed in Scilit:
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