Structure–activity relationships of arylbenzofuran H3 receptor antagonists
- 1 May 2005
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (10) , 2559-2563
- https://doi.org/10.1016/j.bmcl.2005.03.047
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological Characterization and Broad Preclinical Efficacy in Cognition and Schizophrenia of a Potent and Selective Histamine H3 Receptor AntagonistThe Journal of Pharmacology and Experimental Therapeutics, 2005
- Pharmacological Properties of ABT-239 [4-(2-{2-[(2 R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and Selective Histamine H3 Receptor Antagonist with Drug-Like PropertiesThe Journal of Pharmacology and Experimental Therapeutics, 2005
- Selective histamine H3 receptor antagonists for treatment of cognitive deficiencies and other disorders of the central nervous systemPharmacology & Therapeutics, 2004
- 1-Alkyl-4-acylpiperazines as a New Class of Imidazole-Free Histamine H3 Receptor AntagonistsJournal of Medicinal Chemistry, 2004
- Recent advances in histamine H3/H4receptor ligandsExpert Opinion on Therapeutic Patents, 2003
- Design, Synthesis, and Structure−Activity Relationships of Acetylene-Based Histamine H3 Receptor AntagonistsJournal of Medicinal Chemistry, 1999
- 3-(2-Benzofuranyl)quinuclidin-2-ene Derivatives: Novel Muscarinic AntagonistsJournal of Medicinal Chemistry, 1996
- An efficient and selective method for the preparation of iodophenolsThe Journal of Organic Chemistry, 1990
- Copper(I)-activated addition of Grignard reagents to nitriles. Synthesis of ketimines, ketones, and aminesThe Journal of Organic Chemistry, 1987
- Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptorNature, 1983