4-Hydroxy-L-threonine, a committed precursor of pyridoxol (vitamin B6)
- 1 January 1995
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 13,p. 1339-1340
- https://doi.org/10.1039/c39950001339
Abstract
Having established in an earlier experiment that, in Escherichia coli, 4-hydroxy-L-threonine [(2S,3S)-2-amino-3,4-dihydroxybutanoic acid] lies on the route from glucose to vitamin B6, it is now demonstrated that the amino acid serves as a precursor of pyridoxol, since 13C NMR spectroscopy shows that the intact C-2,3 bond of [2,3-13C2]-4-hydroxy-L-threonine 2 becomes the C-5,6 bond of pyridoxol 1.Keywords
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