Depression of Circulating Interferon Response in Balb/c Mice after Urethan Treatment
- 27 January 1967
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 155 (3761) , 482-484
- https://doi.org/10.1126/science.155.3761.482
Abstract
Urethan, when given to female Balb/c mice, impaired the capacity of these animals to produce circulating interferon. The effect appeared rapidly after a single injection of either 1 or 1.5 milligrams of urethan per gram of body weight and was of short duration. The possibility that this inhibition of the production of interferon plays a role in the enhancement of viral leukemia by urethan should now be considered.Keywords
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