Efficient Synthesis of α-C-Galactosyl Ceramide Immunostimulants: Use of Ethylene-Promoted Olefin Cross-Metathesis
- 1 October 2004
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 6 (22) , 4077-4080
- https://doi.org/10.1021/ol0482137
Abstract
Olefin cross-metathesis has been used to prepare α-C-galactosylceramide derivatives. The metathesis process merged vinyl and propenyl glycosides with vinyl derivatives of phytosphingosine. The use of ethylene enhanced the yield of the methathesis step.Keywords
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