A review of approaches to the analysis of 3-nitrotyrosine
Open Access
- 7 November 2003
- journal article
- review article
- Published by Springer Nature in Amino Acids
- Vol. 25 (3-4) , 351-361
- https://doi.org/10.1007/s00726-003-0022-z
Abstract
Our understanding of in vivo tyrosine nitration has been confounded by problems associated with the analytical approaches that have been employed to quantify 3-nitroyrosine (3-NT). Trace analysis is a demanding task under the best of circumstances, but 3-NT offers some special concerns. This review examines some of these concerns and discusses approaches to ensuring that carefully validated analytical data are generated.Keywords
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