A PECULIAR DISCOLORATION OF THE SKIN

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Abstract
In 1922, I1reported two cases of pigmentation of the face as the result of using cosmetic containing calomel. At the time, this seemed a rather rare phenomenon, and was thought to be dependent on a personal chemical peculiarity of the perspiration. Subsequent experience has demonstrated that such a peculiarity is not especially rare, if we may thus explain the pigmentation. Within the last year, I have seen thirteen more cases, in all of which the distribution of the discoloration was very striking and readily recognizable. It is not uncommon to have one of the youngest dermatologic assistants make the diagnosis. Curiously enough, however, the general clinician rarely suspects the true nature of the pigmentation, but looks on it as an early addisonian pigmentation, an evidence of fatigue attendant on nervous exhaustion, or cardiac, hepatic or other chronic diseases, or disregards it entirely. When it was first recognized that

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