The pathogenesis of a single challenge dose ofHaemonchus contortusin lambs under six months of age

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Abstract
The pathogenesis of H. contortus infection in lambs under 6 months of age challenged orally with 10,000 third stage infective larvae is described. The development of the parasite and its relationship to haematological and pathological changes are discussed, with particular reference to specific cellular mobilizations, and detailed descriptions are given of the haematology and parasitology, gross pathology and histopathology at 4, 7, 12, 18, 22 and 35 days after infection. Dramatic changes had developed by day 12.