Decrease of intracellular chloride activity by furosemide in frog retinal pigment epithelium
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Current Eye Research
- Vol. 3 (4) , 673-675
- https://doi.org/10.3109/02713688409003071
Abstract
We found that intracellular chloride activity in frog retinal pigment epithelium (RPE) was significantly higher than predicted from the equilibrium distribution across the cell membranes. When transepithelial chloride transport was inhibited by furosemide intracellular chloride activity decreased and approached electrochemical equilibrium. These data indicate that RPE possesses an active, furosemide-sensitive chloride transport across the apical membrane.Keywords
This publication has 6 references indexed in Scilit:
- Intracellular ion activities and Cl-transport mechanisms in bullfrog corneal epitheliumAmerican Journal of Physiology-Cell Physiology, 1983
- An improved liquid ion exchanger for chloride ion-selective microelectrodesAmerican Journal of Physiology-Cell Physiology, 1981
- Intracellular potassium activity of isolated human and rabbit corneal epitheliumExperimental Eye Research, 1979
- Active transport of ions across frog retinal pigment epitheliumExperimental Eye Research, 1977
- Aspects of electrolyte transport in frog pigment epitheliumExperimental Eye Research, 1973
- Potential, Current, and Ionic Fluxes across the Isolated Retinal Pigment Epithelium and ChoroidThe Journal of general physiology, 1966