High Concentrations of Oxytocin in Hypophysial Portal Plasma*
- 1 April 1984
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 114 (4) , 1216-1218
- https://doi.org/10.1210/endo-114-4-1216
Abstract
Hypophyseal portal blood was collected from pentobarbital-anesthetized male rats, and the content of oxytocin (OT) was measured by radioimmunoassay. The concentration of OT in portal plasma was 1.88 .+-. 0.48 ng/ml (standard error of the mean) and was at least 15 times higher than the concentration of OT in peripheral plasma samples from the same rats. Dilutions of portal plasma produced a displacement curve parallel to those of synthetic OT and posterior lobe extract. The data support a possible role for OT as a hypothalamic-releasing hormone.This publication has 4 references indexed in Scilit:
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