Proton editing and imaging of lactate
- 1 April 1991
- journal article
- Published by Wiley in NMR in Biomedicine
- Vol. 4 (2) , 73-80
- https://doi.org/10.1002/nbm.1940040208
Abstract
Highly specific NMR assays for the detection, quantitation and imaging of lactate in vivo are described. Applications in animals include tumor monitoring, the determination of hypoxic cell distribution and the demonstration of the efficacy of tumor‐sensitizers. The methods (GE‐DQCOSY and GE‐HMQC) may be particularly useful in heteronuclear NMR in vivo.Keywords
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