A clinico-pathological study of adult histiocytosis X involving the brain.
Open Access
- 1 September 1993
- journal article
- case report
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 56 (9) , 1008-1012
- https://doi.org/10.1136/jnnp.56.9.1008
Abstract
Adult histiocytosis X involving the CNS caused progressive spastic paraparesis. The diagnosis was made by immunoreactive anti-S100 protein antibody staining and from the presence of Birbeck granules in biopsy specimens of skin lesions. Neuropathological examination showed massive proliferation and infiltration of S-100 containing histiocyte-like cells and reactive astrocytes throughout the CNS.Keywords
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