INCREASED CLEARANCE OF PHENYTOIN AS THE PRESENTING FEATURE OF INFECTIOUS MONONUCLEOSIS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 2  (4) , 355-357
Abstract
A 19 yr old man with posttraumatic seizures under good control with phenytoin, 500 mg/day, presented with 3 seizures. His blood level of phenytoin, previously in a therapeutic range, was 4.2 .mu.g/ml. No systemic or laboratory evidence of infectious mononucleosis was found. Ten days later, the blood picture became compatible with infectious mononucleosis, at which time his phenytoin clearance returned to normal.

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