The non-essential nature of tyrosine

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Abstract
To establish the indispensability or otherwise of tyrosine, the bulk of it was removed from protein hydrolysates by crystallization, the remainder by destruction with potato-tyrosinase, and the tyrosine-free residue was fed to young rats. Trypsin- or acid-hydrolysed casein so treated (the latter with tryptophane supplements), gave equally good growth when made up into a diet, whether tyrosine was added or not. The phenyl-alanine-free goose-feather keratin was also hydrolzed by both H2SO4 and HC1, the tyrosine similarly removed, and the residue made up into diets supplemented with tryptophane. Alone, or with supplements of tyrosine or phenyl-alanine, these diets would not support growth, probably because the hydrolysate was repulsive in nature. It is concluded that tyrosine is not essential, but that phenyl-alanine may be.

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