A 4-Dimethylaminopyridine-Catalyzed Aminolysis of β-Ketoesters. Formation of β-Ketoamides
- 1 January 1989
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1989 (10) , 753-755
- https://doi.org/10.1055/s-1989-27383
Abstract
Alkyl 3-oxoalkanoates (ß-ketoesters) react with amines in the presence of a catalytic amount of 4-dimethylaminopyridine (DMAP) under mild conditions to form 3-oxoalkanamides (ß-ketoamides) in good yields.Keywords
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