Protection against a Malaria Challenge by Sporozoite Inoculation
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Open Access
- 30 July 2009
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 361 (5) , 468-477
- https://doi.org/10.1056/nejmoa0805832
Abstract
An effective vaccine for malaria is urgently needed. Naturally acquired immunity to malaria develops slowly, and induction of protection in humans can be achieved artificially by the inoculation of radiation-attenuated sporozoites by means of more than 1000 infective mosquito bites.Keywords
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