Relationship between elongation factor 1- and elongation factor 2-dependent guanosine triphosphatase activities of ribosomes. Inhibition of both activities by ricin
- 1 June 1975
- journal article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 148 (3) , 447-451
- https://doi.org/10.1042/bj1480447
Abstract
The elongation factor 1- and elongation factor 2-dependent GTPase (guanosine triphosphatase) activities of ribosomes are inhibited by ricin, a toxic protein known to inactivate the 60S ribosomal subunit. It is suggested that also in eukaryotic ribosomes a “GTPase site’, located on the larger subunit, is common to the two elongation factors.Keywords
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