Antiproliferative Constituents in Umbelliferae Plants. IV. Constituents in the Fruits of Anthriscus sylvestris HOFFM.

1 January 1998

journal article
Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN

Vol. 46 (5) , 875-878
https://doi.org/10.1248/cpb.46.875

Abstract

The constituents in the fruit of Anthriscus sylvestris Hoffm. were investigated, and four lignans [deoxypodophyllotoxin, morelensin, (-)-deoxypodorhizone, and (-)-hinokinin], one phenylpropanoid [1-(3',4'-dimethoxyphenyl)-1 xi-hydroxy-2-propene], two phenylpropanoid esters [3',4'-dimethoxycinnamyl (Z)-2-angeloyloxymethyl-2-butenoate and 3',4'-dimethoxycinnamyl (Z)-2-tigloyloxymethyl-2-butenoate], and one polyacetylenic compound (falcarindiol) were isolated. Their antiproliferative activity against MK-1, HeLa and B16F10 cell lines is reported.

Keywords

PHENYLPROPANOID
ANTHRISCUS SYLVESTRIS
ANTIPROLIFERATIVE
CONSTITUENTS
BUTENOATE
SYLVESTRIS HOFFM
DIMETHOXYCINNAMYL

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