Cholesterol Signaling at the Endoplasmic Reticulum Occurs in npc1−/− but Not in npc1−/−, LDLR−/− Mice
- 1 June 2001
- journal article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 284 (2) , 326-330
- https://doi.org/10.1006/bbrc.2001.4971
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- Niemann-Pick Type C1 (NPC1) Overexpression Alters Cellular Cholesterol HomeostasisJournal of Biological Chemistry, 2000
- Cholesterol Movement in Niemann-Pick Type C Cells and in Cells Treated with AmphiphilesJournal of Biological Chemistry, 2000
- Cholesterol accumulation in tissues of the Niemann-Pick type C mouse is determined by the rate of lipoprotein-cholesterol uptake through the coated-pit pathway in each organProceedings of the National Academy of Sciences, 1999
- Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis GeneScience, 1997
- Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugsPublished by Elsevier ,1994
- The Niemann-Pick C lesion and its relationship to the intracellular distribution and utilization of LDL cholesterolBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
- Regulation of low density lipoprotein receptor and 3-hydroxy-3-methyl-glutaryl-CoA reductase activities are differentially affected in Niemann–Pick type C and type D fibroblastsBiochemistry and Cell Biology, 1993
- Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.Journal of Clinical Investigation, 1993
- Defective activity of acyl-CoA:cholesterol O-acyltransferase in Niemann-Pick type C and type D fibroblastsBiochemical Journal, 1989
- Correction of sphingomyelinase deficiency in Niemann‐Pick type C fibroblasts by removal of lipoprotein fraction from culture mediaJournal of Inherited Metabolic Disease, 1988