Secondary Constrictions in Human Chromosomes

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Abstract
Human leukocyte cultures have been studied for the location of secondary constrictions and their frequency of occurrence. The constrictions appear most frequently in chromosomes 9 and 1, less frequently in 2, 4L, 6L, 11, 13, 16 and rarely in 3, 5L, 6S, 17, 19 and 21. In general, only one homolog bears the constriction with the exception of numbers 9 and 1. The concentration of mitotic accumulating agent appears to affect the occurrence of secondary constrictions. Cultures treated with 5-bromodeoxyuridine show many of the normally-occurring constrictions and in addition other regularly-occurring morphological markers of a similar nature.

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