Effect of Total-Body X-Irradiation on Relative Turnover of Nucleic Acid Phosphorus.
- 1 December 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (3) , 698-701
- https://doi.org/10.3181/00379727-81-19992
Abstract
The incorporation of P32 into DNA; nuclear PNA (nPNA), and cytoplasmic PNA (cPNA) of liver was measured in rats which had been exposed to 2500r total body X-irradiation and in mice which had been exposed to 600r total body X-irradiation. It was found that the incorporation of P32 into cPNA was increased in all cases, while into DNA and nPNA it was depressed. In the Sprague-Dawley rats an increase in the weights of the liver was observed concurrent with the increase in cPNA specific activity. A possible interrelationship between protein and cPNA synthesis has been discussed.Keywords
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- EFFECT OF X-RAYS ON NUCLEIC ACID AND PROTEIN SYNTHESIS1951
- THE INTRACELLULAR HETEROGENEITY OF PENTOSE NUCLEIC ACID AS EVIDENCED BY THE INCORPORATION OF RADIOPHOSPHORUS1950
- THE SEPARATION OF PENTOSE AND DESOXYPENTOSE NUCLEIC ACIDS FROM ISOLATED MOUSE LIVER CELL NUCLEI1950