New antitumor antibiotics, OS-4742 A1, A2, B1 and B2 produced by a strain of Streptomyces.
- 1 January 1977
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 30 (11) , 908-916
- https://doi.org/10.7164/antibiotics.30.908
Abstract
New antibiotics, OS-4742 A1, A2, B1 and B2, were isolated from the culture broth of the strain OS-4742, which was designated as Streptomyces matensis subsp. vineus. These compounds have anthracycline chromophores and sugar moieties, but do not contain nitrogen. They possess antimicrobial activities against Gram-positive bacteria and antitumor activities against S-180 solid tumor on mice.Keywords
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