Ultraviolet light inhibition of oriented, fibrin formation in psoriasis

Abstract
Radially-oriented fibrin crystallization was induced by incubation of blood from psoriatic patients with killed Pseudomonas aeruginosa. The phenomenon was inhibited by irradiation of the buffy coat in plasma with UV-B. It was not inhibited by UV-A unless trioxsalen had been added. Addition of UV-A-irradiated plasma to non-irradiated buffy coat also inhibits the fibrin formation.