Association between plaque accumulation and Langerhans cell numbers in the oral epithelium of attached gingiva
- 1 August 1982
- journal article
- research article
- Published by Wiley in Journal of Clinical Periodontology
- Vol. 9 (4) , 297-304
- https://doi.org/10.1111/j.1600-051x.1982.tb02096.x
Abstract
After gingival health had been achieved in four subjects they were instructed to cease all oral hygiene measures. At 0, 8 and 21 days Plaque and Gingival Indices were recorded and gingival biopsies were removed from the buccal aspect of a first molar. Frozen sections of the gingival oral epithelium were stained for ATPase and 5′‐nucleotidase to determine the number of Langerhans cells in a defined cross‐sectional area. It was found that, as plaque accumulated, there was a statistically significant increase in the number of Langerhans cells in oral epithelium, particularly in the stratum spinosum. These results indicate that dental plaque can elicit a response in Langerhans cells located in the oral epithelium of the gingiva.Keywords
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