Globin Lentiviral Vector Insertions Can Perturb the Expression of Endogenous Genes in β-thalassemic Hematopoietic Cells
Open Access
- 1 March 2008
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 16 (3) , 525-533
- https://doi.org/10.1038/sj.mt.6300394
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivoJournal of Clinical Investigation, 2007
- Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapyJournal of Clinical Investigation, 2007
- What Are the Consequences of the Fourth Case?Molecular Therapy, 2007
- Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cellsBlood, 2005
- Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vectorThe Lancet, 2004
- RTCGD: retroviral tagged cancer gene databaseNucleic Acids Research, 2004
- LMO2 -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1Science, 2003
- Occurrence of leukaemia following gene therapy of X-linked SCIDNature Reviews Cancer, 2003
- Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 DiseaseScience, 2000
- Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell linesCell, 1988