Histochemical Studies of Carboxylic Esterase Activity in Fasciola hepatica

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Abstract
A histochemical study has been made of the distribution of carboxylic esterase activity in adult F. hepatica. By the use of specific substrates and inhibitors 3 distinct esterases have been localized in various tissues within the worm. In general, acetylcholinesterase activity is found in the tegument and neuromuscular tissues, nonspecific esterases in the reproductive structures, and a resistant-type indoxyl esterase occurs in the gut epithelium. The results are compared with biochemical findings and the role of carboxylic esterases in the liver fluke is discussed.

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