Solubility Coefficients of Teflurane in Various Biological Media
Open Access
- 1 March 1964
- journal article
- research article
- Published by Wolters Kluwer Health in Anesthesiology
- Vol. 25 (2) , 223-225
- https://doi.org/10.1097/00000542-196403000-00015
Abstract
Solubility coefficients (gamma) for teflurane were measured and found to be 0.32 for water, 0.60 for blood, and 29.0 for oil. Tissue/gas values were gray matter, 1.08; white matter, 1.15; liver, 1.02; and muscle, 2.26. Tissue/blood coefficients are muscle, 2.8; gray matter, 1.8; white matter, 1.9; and liver, 1.7. Reduction in temperature was found to increase solubility in both water and oil. From these figures one may predict that teflurane, compared to cyclopropane, should be almost as rapid in induction, slightly slower in recovery, and more potent.Keywords
This publication has 1 reference indexed in Scilit:
- A Comparative Study of Halothane and Halopropane AnesthesiaAnesthesiology, 1963