Assay for amoxycillin in urine using derivative spectrophotometry
- 1 April 1992
- journal article
- Published by Hindawi Limited in Journal of Clinical Pharmacy & Therapeutics
- Vol. 17 (2) , 101-105
- https://doi.org/10.1111/j.1365-2710.1992.tb01275.x
Abstract
Three derivative spectrophotometric methods have been described for the assay of amoxycillin in urine. The methods were based on the amplitude measurements of second derivative (D2), first derivative difference (ΔD1) or second derivative difference (ΔD2) curves. These values were linearly correlated to the amoxycillin concentration in the range of 0.2–1.0 mg% with negligible intercepts. The absolute recovery from urine specimens was found to be 98%. The within-day and between-day precision were satisfactory.Keywords
This publication has 10 references indexed in Scilit:
- Determination of nitrofurantoin in urine by derivative spectroscopyInternational Journal of Pharmaceutics, 1986
- Determination of ethinyloestradiol in the presence of norethisterone by derivative-difference spectrophotometryInternational Journal of Clinical Pharmacy, 1985
- High performance liquid chromatographic determination and pharmacokinetic investigation of amino-penicillins and their metabolites in man.CHEMICAL & PHARMACEUTICAL BULLETIN, 1981
- High-Pressure Liquid Chromatographic Determination of Amoxicillin in UrineJournal of Pharmaceutical Sciences, 1979
- A simple, rapid fluorimetric assay of amoxycillin in plasmaClinica Chimica Acta; International Journal of Clinical Chemistry, 1977
- Bioavailability of Ampicillin and Amoxicillin in Fasted and Nonfasted SubjectsJournal of Pharmaceutical Sciences, 1977
- Rapid Sensitive Fluorometric Analysis of Cephalosporin AntibioticsJournal of Pharmaceutical Sciences, 1977
- Fluorometric determination of amoxicillin.CHEMICAL & PHARMACEUTICAL BULLETIN, 1977
- A simple chemical method for the assay of amoxycillin in serum and urineClinica Chimica Acta; International Journal of Clinical Chemistry, 1976
- Numerical error analysis of derivative spectrometry for the quantitative analysis of mixturesAnalytical Chemistry, 1976