The Determination of Phenolsulphonphthalein with the Photoelectric Colorimeter and its Application to the “Phthalein Elimination Curve”

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Abstract
The details of a photoelectric method for the detn. of phenolsulphonphthalein are presented. Evidence is presented to show that with the admn. of intraven. fluids preliminary to the phenolsulphonphthalein test, both in health and with renal disease, maximal excretion of dye always occurs in the first collection period. Delayed "phthalein elimination curves" with maximal excretion of the dye in later periods can be converted to curves with maximal excretion in the first collection period by the preliminary admn. of intraven. fluids. The possible mechanisms involved are discussed.