Immunologic reactivity of lymph nodes regional to prostatic cancer: Preliminary observations

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Abstract
Regional pelvic lymph nodes from 9 patients with prostatic carcinoma were investigated for in vitro immunologic reactivity to T and B cell mitogens. Regional lymph node lymphocytes were significantly more reactive when obtained from nodes morphologically displaying T and B lymphorplasia than from nodes that histologically appeared normal or depleted of lymphocytes. The data suggest that a morphologic evaluation of lymph nodes regional to prostate cancer may reflect the patient's antitumor immune response.