A convenient method for the synthesis of macrocyclic tetra-amides by double condensation reaction
- 1 January 1984
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 5,p. 1115-1118
- https://doi.org/10.1039/p19840001115
Abstract
A facile condensation reaction between bifunctional amines and carboxylic acid derivatives has been found to be very efficient for the formation of macrocyclic tetra-amide rings, and tetralactams with 33- to 37-membered rings were readily synthesized in good yields (60–90%).This publication has 0 references indexed in Scilit: